SPOKE 2

Connecting patients and therapists through adaptive environments and intelligent sensors to enhance proximity medicine

Innovative sensors, devices, and digital tools for the early assessment and treatment of environmental factors, lifestyles, and pathological conditions in populations of fragile and chronic patients.

SPOKE LEADER

Guido Cavaletti

Università degli Studi di Milano Bicocca

obbiettivo spoke 2

Objectives

  • Development of wearable sensors, (e.g. patches for the control of measurable biochemical markers, breath-monitoring devices), portable and environmental to monitor in real time both the clinical parameters of patients and the environmental risks involved in the onset of pathological conditions in fragile and chronic populations.
  • Generation of technological platforms for the control of biological risk contamination (i.e. nanoparticles and metagenomic platforms for the analysis of microbial identities) and their use related to the entire patient management process (from triage to therapeutic plan).

Methodologies

Spoke 2 uses technological innovations to detect early relapse indicators in chronic diseases. Artificial intelligence (AI) driven devices and platforms will be generated allowing real-time monitoring of patient conditions and environmental hazards, and prediction of events potentially dangerous for people.

Virtual reality (VR) and smart-assisted devices (e.g. virtual environment and digital motion capture)

Technologies to monitor cardiovascular diseases (e.g. devices for performing wearable ECG on T-shirts and AI-assisted platforms for patient assessment)

Intelligent medical devices and platforms (In/Ga biosensors) integrated into functionalized printed patches and biomaterials to detect representative biomarkers (e.g. cholesterol, PCR, glucose)

Cure points based on multi-functional colloidal nanoparticles (conjugated nanoparticles) and DNA-omics to detect and quantify bio environmental and human hazards (microbial pathogens)

State-of-the-art lights - systems for cleaning environments contaminated with microbial pathogens

Spoke 2

Pilot-Based Programme

Pilot 2.1, Pilot 2.4 and Pilot 2.5

They are dedicated to environmental control (ambulatory and home care centers) and focused respectively on the implementation of home care routes and on quality control of care centers in case of biological risk.

Pilot 2.2, Pilot 2.3, Pilot 2.6 and Pilot 2.7

They are dedicated to generate and collect patient data to maximise and make available innovative methods for early diagnosis. Activities related to innovative therapies for orphan tumours will integrate telemedicine methodologies from the outset, providing for the possibility of telemonitoring (tele-follow-up) after treatment.

All pilots will include the evaluation and validation of AI-based platforms to generate data that can be used in clinical settings and in connection with the health system infrastructures.
SPOKE 2

Contacts

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Ministero dell'Università e della Ricerca Italia Domani Piano Nazionale per gli investimenti complementari al PNRR ANTHEM